A new wave in the genetics of psychiatric disorders: the copy number variant tsunami
R Joober, P Boksa - Journal of Psychiatry and Neuroscience, 2009 - jpn.ca
Because genes are major determinants of psychiatric disorders, our community is hoping
that, as in many other branches of medicine, 1 molecular genetics will lead to important …
that, as in many other branches of medicine, 1 molecular genetics will lead to important …
Copy number variants: a new molecular frontier in clinical psychiatry
D Moreno-De-Luca, JF Cubells - Current psychiatry reports, 2011 - Springer
Molecular genetic research, building on genetic epidemiology, has provided the field of
psychiatry with a host of exciting advances. It is now clear beyond any reasonable doubt that …
psychiatry with a host of exciting advances. It is now clear beyond any reasonable doubt that …
After GWAS: searching for genetic risk for schizophrenia and bipolar disorder
ES Gershon, N Alliey-Rodriguez… - American Journal of …, 2011 - Am Psychiatric Assoc
Ten years ago it was widely expected that the genetic basis of common disease would be
resolved by genome-wide association studies (GWAS), large-scale studies in which the …
resolved by genome-wide association studies (GWAS), large-scale studies in which the …
[HTML][HTML] CNVs: harbingers of a rare variant revolution in psychiatric genetics
D Malhotra, J Sebat - Cell, 2012 - cell.com
The genetic bases of neuropsychiatric disorders are beginning to yield to scientific inquiry.
Genome-wide studies of copy number variation (CNV) have given rise to a new …
Genome-wide studies of copy number variation (CNV) have given rise to a new …
A quarter century of progress in psychiatric genetics
JW Smoller - Harvard review of psychiatry, 2017 - journals.lww.com
Downloaded from by BhDMf5ePHKbH4TTImqenVA+ lpWIIBvonhQl60EtgtdlLYrLzSPu+
hQedJnbNaXBf on 11/27/2023 enabled an “unbiased” search for risk loci by examining …
hQedJnbNaXBf on 11/27/2023 enabled an “unbiased” search for risk loci by examining …
Polygenic heterogeneity: a complex model of genetic inheritance in psychiatric disorders
JJH Rucker, P McGuffin - Biological psychiatry, 2010 - biologicalpsychiatryjournal.com
Shields (1). They proposed, following on from the seminal work of Falconer (2), that what is
inherited is not so much a disorder as a liability to disorder contributed to by multiple genetic …
inherited is not so much a disorder as a liability to disorder contributed to by multiple genetic …
Selected summaries from the XVI World Congress of Psychiatric Genetics, Osaka, Japan, 11–15 October 2008
Abstract The XVI World Congress of Psychiatric Genetics, sponsored by the International
Society of Psychiatric Genetics took place in Osaka, Japan, October 2008. Approximately …
Society of Psychiatric Genetics took place in Osaka, Japan, October 2008. Approximately …
[HTML][HTML] Increasing the clinical psychiatric knowledge base about pathogenic copy number variation
PF Sullivan, MJ Owen - American Journal of Psychiatry, 2020 - Am Psychiatric Assoc
Specific copy number variants (CNVs) have been robustly associated with intellectual
disability, autism, and schizophrenia. Most of the focus in the literature has been on …
disability, autism, and schizophrenia. Most of the focus in the literature has been on …
Brain copy number variants and neuropsychiatric traits
JR Lupski - Biological psychiatry, 2012 - biologicalpsychiatryjournal.com
In this issue of Biological Psychiatry, genomic analysis of patients with neuropsychiatric
disease reveals the presence of rare copy number variants (CNVs) in about 2% of the …
disease reveals the presence of rare copy number variants (CNVs) in about 2% of the …
Polygenicity in psychiatry—like it or not, we have to understand it
MJ Gandal, DH Geschwind - Biological Psychiatry, 2021 - biologicalpsychiatryjournal.com
The subjective and symptomatic basis of psychiatric diagnoses—coupled with high rates of
comorbidity, clinical heterogeneity, and the overwhelming complexity of the human brain …
comorbidity, clinical heterogeneity, and the overwhelming complexity of the human brain …
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