Recently, the interim results of the 1000 Genomes Project were published and revealed that
the genome of an apparently healthy individual contains hundreds of potentially harmful …

Although genome-wide association studies (GWAS), in general, facilitated important
discovery of new biological knowledge about diseases, 1--3 identified variants for …

Current Psychiatry March 2013 26 been a major focus of psychiatric genetics in the past
decade. Technology now allows researchers to simultaneously genotype millions of SNPs …

The human genome project has spurred great enthusiasm in many research communities
and, of special interest to readers of Biological Psychiatry, has raised hope that genetic …

As technology advances, whole genome sequencing (WGS) is likely to supersede other
genotyping technologies. The rate of this change depends on its relative cost and utility …

The genetic architecture of schizophrenia is likely contributed by both common and rare
variants. 1 Recent genome-wide studies have revealed that common variants in the major …

The past decade has been one of unprecedented discovery in psychiatry. Large-scale
genomic studies have identified hundreds of molecular risk factors and illuminated the …

The primary aim of precision medicine is to tailor healthcare more closely to the needs of
individual patients. This requires progress in two areas: the development of more precise …

Psychiatric disorders such as schizophrenia, bipolar disorder, major depressive disorder,
attention-deficit/hyperactivity disorder and autism spectrum disorder are common and result …

The widespread comorbidity among psychiatric disorders demonstrated in epidemiological
studies,,,–is mirrored by non-zero, positive genetic correlations from large-scale genetic …