Should thyroid replacement therapy be considered for patients with treatment-refractory depression?

RT Joffe - Journal of Psychiatry and Neuroscience, 2002 - ncbi.nlm.nih.gov
To submit questions for this regular feature, please send them to the Journal of Psychiatry &
Neuroscience/Revue de psychiatrie & de neuroscience, Canadian Medical Association …

[PDF][PDF] Is the thyroid still important in major depression?

RT Joffe - Journal of Psychiatry and Neuroscience, 2006 - jpn.ca
For more than a century, there have been rich descriptions in the clinical literature of
prominent depressive symptoms in patients with thyroid disease, particularly clinical …

[HTML][HTML] Thyroid hormone use in mood disorders: revisiting the evidence

B Singh, V Sundaresh - The Journal of Clinical Psychiatry, 2022 - legacy.psychiatrist.com
Alterations in thyroid functioning have been of long-standing interest in the research and
treatment of depressive disorders. Thyroid hormones may play a role in mood regulation by …

Thyroid hormones in depressive disorders: a reappraisal of clinical utility

RA Lasser, RJ Baldessarini - Harvard review of psychiatry, 1997 - Taylor & Francis
Centuries of clinical observation suggest a connection between thyroid function and
behavior. Advances in neuroendocrinology of the hypothalamic-pituitary-thyroid (HPT) axis …

[HTML][HTML] Antidepressant-resistant depression in patients with comorbid subclinical hypothyroidism or high-normal TSH levels

BM Cohen, BR Sommer… - American Journal of …, 2018 - Am Psychiatric Assoc
Thyroid and mood disorders are both common and may co-occur in the same person, and
psychiatrists must optimize treatment for patients with these comorbid disorders. In many …

Peripheral thyroid dysfunction in depression

KN Fountoulakis, S Kantartzis, M Siamouli… - The World Journal of …, 2006 - Taylor & Francis
The involvement of the thyroid gland and thyroid hormones is generally believed to be
important in the aetiopathogenesis of major depression. Major support comes from studies …

Thyroid hormone treatment in the management of treatment‐resistant unipolar depression: a systematic review and meta‐analysis

R Lorentzen, JN Kjaer, SD Østergaard… - Acta Psychiatrica …, 2020 - Wiley Online Library
Background Treatment with thyroid hormones is occasionally used in the management of
treatment‐resistant depression. However, the evidence supporting this treatment is not fully …

Novel uses of thyroid hormones in patients with affective disorders

AJ Prange Jr - Thyroid, 1996 - liebertpub.com
Hormones of the thyroid axis have been used to treat patients with any of several mental
illnesses. However, in recent decades interest has focused almost exclusively on …

Routine screening of thyroid function in patients hospitalized for major depression or dysthymia?

DM Ordas, LA Labbate - Annals of clinical psychiatry, 1995 - Taylor & Francis
Our objective was to examine the clinical practice of testing thyroid function in a mixed
community and referral psychiatry inpatient unit. We evaluated (1) the frequency of ordering …

Does Thyroid Hormone Have a Role as Adjunctive Therapy in Depression? 1

IMD Jackson - Thyroid, 1996 - liebertpub.com
Depression is associated with abnormalities of the thyroid axis, but the role of thyroid
hormone therapy is controversial. In patients presenting with depression, the thyroid status …