Diabetes mellitus during pregnancy and increased risk of schizophrenia in offspring: a review of the evidence and putative mechanisms

RJ Van Lieshout, LP Voruganti - Journal of Psychiatry and Neuroscience, 2008 - jpn.ca
Objective: To identify converging themes from the neurodevelopmental hypothesis of
schizophrenia and the pathophysiology of diabetic pregnancy and to examine mechanisms …

Prenatal exposure to gestational diabetes mellitus as an independent risk factor for long-term neuropsychiatric morbidity of the offspring

KN Sacks, M Friger, I Shoham-Vardi, H Abokaf… - American journal of …, 2016 - Elsevier
Background The reported rates of gestational diabetes mellitus are constantly escalating
and little is known about long-term complications in the offspring. Evidence from the field of …

Animal models of obstetric complications in relation to schizophrenia

P Boksa - Brain Research Reviews, 2004 - Elsevier
Epidemiological studies have provided strong evidence that exposure to obstetric
complications is associated with an increased risk for later development of schizophrenia …

Prenatal factors in schizophrenia

S King, A St-Hilaire… - Current Directions in …, 2010 - journals.sagepub.com
The purpose of this review is to summarize the current state of knowledge on how
nongenetic factors occurring before, during, or soon after birth are related to schizophrenia …

Do hypertension and diuretic treatment in pregnancy increase the risk of schizophrenia in offspring?

HJ Sørensen, EL Mortensen… - American Journal of …, 2003 - Am Psychiatric Assoc
OBJECTIVE: Diuretics prescribed after the first trimester for treatment of hypertension in
pregnant women may interfere with normal plasma volume expansion and cause volume …

The association between gestational diabetes mellitus, antipsychotics and severe mental illness in pregnancy: A multicentre study

M Galbally, J Frayne, SJ Watson… - Australian and New …, 2020 - Wiley Online Library
Background There have been conflicting findings for severe mental illnesses and the risk for
gestational diabetes mellitus (GDM). Outside of pregnancy, both severe mental illnesses …

Obstetrical complications and subsequent schizophrenia in adolescent and young adult offsprings: is there a relationship?

G Boog - European Journal of Obstetrics & Gynecology and …, 2004 - Elsevier
Schizophrenia is a psychiatric disease affecting around 1% of the population, the negative
signs of which are correlated with inactivity of the prefrontal dorsolateral cortex, while an …

[HTML][HTML] Gestational diabetes exacerbates maternal immune activation effects in the developing brain

KM Money, TL Barke, A Serezani, M Gannon… - Molecular …, 2018 - nature.com
Maternal inflammation and diabetes increase the risk for psychiatric disorders in offspring.
We hypothesized that these co-occurring risk factors may potentiate each other. To test this …

Antipsychotic use during pregnancy and the risk of gestational diabetes mellitus: a systematic review

F Uguz - Journal of clinical psychopharmacology, 2019 - journals.lww.com
Purpose This study aimed to review the current literature examining a potential relationship
between the use of antipsychotic drugs during pregnancy and gestational diabetes mellitus …

On the nature and mechanisms of obstetric influences in schizophrenia: a review and synthesis of epidemiologic studies

TD Cannon - International Review of Psychiatry, 1997 - Taylor & Francis
Obstetric complications are robust correlates of schizophrenia, but it remains controversial
whether more than one neurally-disruptive mechanism is involved and whether such …