Monoamine oxidase-A polymorphisms might modify the association between the dopamine D2 receptor gene and alcohol dependence

SY Huang, WW Lin, FJ Wan, AJ Chang, HC Ko… - Journal of Psychiatry and …, 2007 - jpn.ca
Objective: Low monoamine oxidase (MAO) activity and the neurotransmitter dopamine are 2
important factors in the development of alcohol dependence. MAO is an important enzyme …

Possible interaction between MAOA and DRD2 genes associated with antisocial alcoholism among Han Chinese men in Taiwan

TJ Wang, SY Huang, WW Lin, HY Lo, PL Wu… - Progress in Neuro …, 2007 - Elsevier
Both monoamine oxidase A (MAOA) and dopamine D2 receptor (DRD2) genes have been
considered as candidate genes for antisocial personality disorder with alcoholism …

Possible interaction of alcohol dehydrogenase and aldehyde dehydrogenase genes with the dopamine D2 receptor gene in anxiety‐depressive alcohol dependence

SY Huang, WW Lin, HC Ko, JF Lee… - Alcoholism: Clinical …, 2004 - Wiley Online Library
Background: The role of the dopamine D2 receptor (DRD2) gene in the development of
alcohol abuse or dependence is controversial. The controversy is due in part to the …

Association of monoamine oxidase A alleles with alcoholism among male Chinese in Taiwan.

YP Hsu, EW Loh, WJ Chen, CC Chen… - The American journal …, 1996 - europepmc.org
Objective The role of monoamine oxidase (MAO) in alcoholism was assessed by genetic
association studies separately in five ethnic groups in Taiwan. Method Restriction fragment …

Association analysis of the dopamine receptor D2 (DRD2) SNP rs1076560 in alcoholic patients

T Sasabe, A Furukawa, S Matsusita, S Higuchi… - Neuroscience …, 2007 - Elsevier
The dopamine system plays a well-established role in alcoholism. In this study, we
examined the association between the single-nucleotide polymorphism (SNP) rs1076560 of …

Association between monoamine oxidase gene polymorphisms and smoking behaviour in Chinese males

Y Jin, D Chen, Y Hu, S Guo, H Sun, A Lu… - International Journal …, 2006 - academic.oup.com
Monoamine oxidase (MAO) is a critical metabolic enzyme of dopamine, which is a key
neurotransmitter of the mesolimbic reward pathway in the human brain. Consequently, the …

Association Study Between Genetic Polymorphisms in the 14–3‐3 η Chain and Dopamine D4 Receptor Genes and Alcoholism

H Ishiguro, T Saito, H Shibuya… - Alcoholism: Clinical and …, 2000 - Wiley Online Library
Background: The dopaminergic system may be involved in the development of alcoholism.
As part of our ongoing studies on the association between alcoholism and dopaminergic …

No evidence of association between structural polymorphism at the dopamine D3 receptor locus and alcoholism in the Japanese

S Higuchi, T Muramatsu, S Matsushita… - American journal of …, 1996 - Wiley Online Library
Dopaminergic systems mediate reward mechanisms and are involved in reinforcing self‐
administration of dependence‐forming substances, including alcohol. Studies have reported …

Alcoholism, ALDH2* 2 allele and the A1 allele of the dopamine D2 receptor gene: an association study

S Matsushita, T Muramatsu, M Murayama, J Nakane… - Psychiatry …, 2001 - Elsevier
The inactive form of aldehyde dehydrogenase-2 (ALDH2) is regarded as a protective factor
against the development of alcoholism, and alcoholics with inactive ALDH2 are considered …

MAOA Interacts With the ALDH2 Gene in Anxiety–Depression Alcohol Dependence

SY Lee, CY Hahn, JF Lee, SY Huang… - Alcoholism: Clinical …, 2010 - Wiley Online Library
Background: Alcohol dependence is usually comorbid with anxiety disorder, depressive
disorder, or both; this comorbidity may increase drinking behavior. We previously …