Genotype over diagnosis in amygdala responsiveness: affective processing in social anxiety disorder

T Furmark, S Henningsson, L Appel, F Åhs… - Journal of Psychiatry and …, 2009 - jpn.ca
Background: Although the amygdala is thought to be a crucial brain region for negative
affect, neuroimaging studies do not always show enhanced amygdala response to aversive …

Amygdala function and 5-HTT gene variants in adolescent anxiety and major depressive disorder

JYF Lau, D Goldman, B Buzas, SJ Fromm, AE Guyer… - Biological …, 2009 - Elsevier
BACKGROUND: Associations between a functional polymorphism in the serotonin
transporter gene and amygdala activation have been found in healthy, depressed, and …

Serotonin transporter polymorphism related to amygdala excitability and symptom severity in patients with social phobia

T Furmark, M Tillfors, H Garpenstrand, I Marteinsdottir… - Neuroscience …, 2004 - Elsevier
A functional polymorphism in the promoter region of the human serotonin transporter (5-
HTT) gene has been related to negative affect and amygdala activity. We studied amygdala …

[HTML][HTML] The serotonin transporter gene polymorphism and the effect of baseline on amygdala response to emotional faces

EAH von dem Hagen, L Passamonti, S Nutland… - Neuropsychologia, 2011 - Elsevier
Previous research has found that a common polymorphism in the serotonin transporter gene
(5-HTTLPR) is an important mediator of individual differences in brain responses associated …

Serotonin transporter gene alters insula activity to threat in social anxiety disorder

H Klumpp, DA Fitzgerald, E Cook, SA Shankman… - …, 2014 - journals.lww.com
Amygdala and insula hyper-reactivity to threat is implicated in social anxiety disorder (SAD)
yet inconsistencies in activation have been reported. One source of variance are individual …

Serotonin transporter genotype modulates subgenual response to fearful faces using an incidental task

EJP O'Nions, RJ Dolan, JP Roiser - Journal of cognitive neuroscience, 2011 - direct.mit.edu
This study assessed the impact of serotonin transporter genotype (5-HTTLPR) on regional
responses to emotional faces in the amygdala and subgenual cingulate cortex (sgACC) …

Volition diminishes genetically mediated amygdala hyperreactivity

DM Schardt, S Erk, C Nüsser, MM Nöthen, S Cichon… - NeuroImage, 2010 - Elsevier
Individuals carrying the short allele of a common polymorphism in the promoter region of the
serotonin transporter gene (5-HTTLPR) exhibit heightened amygdala responses to passive …

[HTML][HTML] How the serotonin transporter 5-HTTLPR polymorphism influences amygdala function: the roles of in vivo serotonin transporter expression and amygdala …

A Kobiella, M Reimold, DE Ulshöfer… - Translational …, 2011 - nature.com
The serotonin transporter-linked promoter region (5-HTTLPR) polymorphism of the serotonin
transporter gene is associated with amygdala response during negative emotion. The aim of …

Emotion specific modulation of automatic amygdala responses by 5-HTTLPR genotype

U Dannlowski, C Konrad, H Kugel, P Zwitserlood… - Neuroimage, 2010 - Elsevier
A functional polymorphism in the serotonin transporter gene (5-HTTLPR) has been reported
to modulate amygdala responsiveness to negative environmental cues. However, it remains …

Cerebral responses to emotional expressions and the development of social anxiety disorder: a preliminary longitudinal study

M Battaglia, A Zanoni, M Taddei, R Giorda… - Depression and …, 2012 - Wiley Online Library
Background Cross‐sectional studies report biased reactivity to facial expressions among
shy children, anxious adolescents, and adults with social anxiety disorder (SAD). It remains …