Key role of the 5-HT1A receptor addressing protein Yif1B in serotonin neurotransmission and SSRI treatment
Background: Altered function of serotonin receptor 1A (5-HT 1A R) has been consistently
implicated in anxiety, major depressive disorder and resistance to antidepressants …
implicated in anxiety, major depressive disorder and resistance to antidepressants …
Targeting of the 5-HT1A serotonin receptor to neuronal dendrites is mediated by Yif1B
D Carrel, J Masson, S Al Awabdh… - Journal of …, 2008 - Soc Neuroscience
The 5-HT1A receptor (5-HT1AR) is the most extensively characterized serotonin (5-HT)
receptor mainly because of its involvement in the mode of action of antidepressants. The 5 …
receptor mainly because of its involvement in the mode of action of antidepressants. The 5 …
The serotonin-1A receptor in anxiety disorders
The serotonin system plays an important role in the neural processing of anxiety. The
involvement of the main inhibitory serotonergic receptor, the serotonin-1A (5-HT1A) subtype …
involvement of the main inhibitory serotonergic receptor, the serotonin-1A (5-HT1A) subtype …
Characterization of 5-HT1A/1B−/− mice: An animal model sensitive to anxiolytic treatments
Selective serotonin (5-HT) re-uptake inhibitors (SSRIs) are commonly used in the treatment
of generalized anxiety disorder in Humans. However, because only few animal models …
of generalized anxiety disorder in Humans. However, because only few animal models …
[HTML][HTML] ERICH3: vesicular association and antidepressant treatment response
Selective serotonin reuptake inhibitors (SSRIs) are standard of care for major depressive
disorder (MDD) pharmacotherapy, but only approximately half of these patients remit on …
disorder (MDD) pharmacotherapy, but only approximately half of these patients remit on …
Loss of adult 5-HT1A autoreceptors results in a paradoxical anxiogenic response to antidepressant treatment
V Turcotte-Cardin, F Vahid-Ansari… - Journal of …, 2019 - Soc Neuroscience
Selective serotonin (5-HT) reuptake inhibitors (SSRIs) are first-line antidepressants but
require several weeks to elicit their actions. Chronic SSRI treatment induces desensitization …
require several weeks to elicit their actions. Chronic SSRI treatment induces desensitization …
Converging translational evidence for the involvement of the serotonin 2A receptor gene in major depressive disorder
AC Petit, G Quesseveur, F Gressier, R Colle… - Progress in Neuro …, 2014 - Elsevier
An association between serotonin 2A receptor (5-HT2AR), encoded by HTR2A gene, and
major depressive disorder (MDD) has been suggested. Here, we combined preclinical and …
major depressive disorder (MDD) has been suggested. Here, we combined preclinical and …
Transcriptional regulation of the 5-HT1A receptor: implications for mental illness
PR Albert - … Transactions of the Royal Society B …, 2012 - royalsocietypublishing.org
The serotonin-1A (5-HT1A) receptor is an abundant post-synaptic 5-HT receptor
(heteroreceptor) implicated in regulation of mood, emotion and stress responses and is the …
(heteroreceptor) implicated in regulation of mood, emotion and stress responses and is the …
Serotonin receptor knockouts: a moody subject
D Julius - Proceedings of the National Academy of …, 1998 - National Acad Sciences
The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) is believed to play a significant
role in determining one's emotional state. Indeed, serotonergic synapses are sites of action …
role in determining one's emotional state. Indeed, serotonergic synapses are sites of action …
[HTML][HTML] Genetic Background Underlying 5-HT1A Receptor Functioning Affects the Response to Fluoxetine
EM Kondaurova, AY Rodnyy, TV Ilchibaeva… - International Journal of …, 2020 - mdpi.com
The influence of genetic background on sensitivity to drugs represents a topical problem of
personalized medicine. Here, we investigated the effect of chronic (20 mg/kg, 14 days, ip) …
personalized medicine. Here, we investigated the effect of chronic (20 mg/kg, 14 days, ip) …