User profiles for Bernard Bioulac
 | Bernard Bioulacprofesseur neurophysiologie université de Bordeaux Verified email at u-bordeaux.fr Cited by 23591 |
Pathophysiology of obsessive–compulsive disorder: a necessary link between phenomenology, neuropsychology, imagery and physiology
Obsessive–compulsive disorder (OCD) is characterized by repetitive intrusive thoughts and
compulsive time-consuming behaviors classified into three to five distinct symptom …
compulsive time-consuming behaviors classified into three to five distinct symptom …
Provocation of obsessive–compulsive symptoms: a quantitative voxel-based meta-analysis of functional neuroimaging studies
Objective: Recent functional magnetic resonance imaging (fMRI) and positron emission
tomography (PET) studies based on the symptom provocation paradigm have explored neural …
tomography (PET) studies based on the symptom provocation paradigm have explored neural …
High-frequency stimulation in Parkinson's disease: more or less?
Deep-brain stimulation at high frequency is now considered the most effective neurosurgical
therapy for movement disorders. An electrode is chronically implanted in a particular area of …
therapy for movement disorders. An electrode is chronically implanted in a particular area of …
Reversal of rigidity and improvement in motor performance by subthalamic high‐frequency stimulation in MPTP‐treated monkeys
In Parkinson's disease the loss of dopaminergic neurons in the substantia nigra is associated
with global disorganization of basal ganglia activity and, in particular, with increased …
with global disorganization of basal ganglia activity and, in particular, with increased …
High-frequency stimulation produces a transient blockade of voltage-gated currents in subthalamic neurons
C Beurrier, B Bioulac, J Audin… - Journal of …, 2001 - journals.physiology.org
The effect of high-frequency stimulation (HFS) of the subthalamic nucleus (STN) was analyzed
with patch-clamp techniques (whole cell configuration, current- and voltage-clamp modes…
with patch-clamp techniques (whole cell configuration, current- and voltage-clamp modes…
Relationship between the appearance of symptoms and the level of nigrostriatal degeneration in a progressive 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine …
…, D Guilloteau, AR Crossman, B Bioulac… - Journal of …, 2001 - Soc Neuroscience
The concept of a threshold of dopamine (DA) depletion for onset of Parkinson's disease
symptoms, although widely accepted, has, to date, not been determined experimentally in …
symptoms, although widely accepted, has, to date, not been determined experimentally in …
Increased D1 dopamine receptor signaling in levodopa‐induced dyskinesia
…, Q Li, S Dovero, N Barthe, BH Bioulac… - Annals of Neurology …, 2005 - Wiley Online Library
Involuntary movements, or dyskinesia, represent a debilitating complication of levodopa
therapy for Parkinson's disease. Although changes affecting D 1 and D 2 dopamine receptors …
therapy for Parkinson's disease. Although changes affecting D 1 and D 2 dopamine receptors …
Morningness/eveningness and the need for sleep
J Taillard, P Philip, B Bioulac - Journal of sleep research, 1999 - Wiley Online Library
The purpose of this study was to determine, in a large sample of adults of all ages (17–80
years), the effect of morningness/eveningness on sleep/wake schedules, sleep needs, sleep …
years), the effect of morningness/eveningness on sleep/wake schedules, sleep needs, sleep …
Subthalamic nucleus neurons switch from single-spike activity to burst-firing mode
C Beurrier, P Congar, B Bioulac… - Journal of …, 1999 - Soc Neuroscience
The modification of the discharge pattern of subthalamic nucleus (STN) neurons from single-spike
activity to mixed burst-firing mode is one of the characteristics of parkinsonism in rat …
activity to mixed burst-firing mode is one of the characteristics of parkinsonism in rat …
Subthalamic high frequency stimulation resets subthalamic firing and reduces abnormal oscillations
High frequency stimulation (HFS) of the subthalamic nucleus (STN) is a well-established
therapeutic approach for the treatment of late-stage Parkinson's disease. Although the …
therapeutic approach for the treatment of late-stage Parkinson's disease. Although the …
