COMT and DAT1 genes are associated with hyperactivity and inattention traits in the 1993 Pelotas Birth Cohort: evidence of sex-specific combined effect
GC Akutagava-Martins, A Salatino-Oliveira… - Journal of psychiatry and …, 2016 - jpn.ca
Background: Attention-deficit/hyperactivity disorder (ADHD) symptoms are dimensionally
distributed in the population. This study aimed to assess the role of the catechol-O …
distributed in the population. This study aimed to assess the role of the catechol-O …
[HTML][HTML] COMT Val158Met Polymorphism and Social Impairment Interactively Affect Attention-Deficit Hyperactivity Symptoms in Healthy Adolescents
SK Millenet, F Nees, S Heintz, C Bach, J Frank… - Frontiers in …, 2018 - frontiersin.org
The dopaminergic system has been shown to have substantial effects on the etiology of
attention-deficit hyperactivity disorder (ADHD). However, while some studies found a …
attention-deficit hyperactivity disorder (ADHD). However, while some studies found a …
COMT Val108/158Met gene variant, birth weight, and conduct disorder in children with ADHD
OBJECTIVE: In a recent study, Thapar and colleagues reported that COMT “gene variant
and birth weight predict early-onset antisocial behavior in children” with attention …
and birth weight predict early-onset antisocial behavior in children” with attention …
Haplotype relative risk study of catechol‐O‐methyltransferase (COMT) and attention deficit hyperactivity disorder (ADHD): Association of the high‐enzyme activity val …
J Eisenberg, G Mei‐Tal, A Steinberg… - American journal of …, 1999 - Wiley Online Library
Attention deficit hyperactivity disorder (ADHD) is a developmental syndrome expressed
along three domains: inattention, hyperactive‐impulsive, and combined type. Both …
along three domains: inattention, hyperactive‐impulsive, and combined type. Both …
Failure to replicate an association between the catechol‐O‐methyltransferase polymorphism and attention deficit hyperactivity disorder in a second, independently …
I Manor, M Kotler, Y Sever, J Eisenberg… - American journal of …, 2000 - Wiley Online Library
Attention deficit hyperactivity disorder (ADHD) is a developmental syndrome expressed
along three domains: inattention, hyperactive‐impulsive, and combined type. Both …
along three domains: inattention, hyperactive‐impulsive, and combined type. Both …
COMT Val158Met polymorphism and socioeconomic status interact to predict attention deficit/hyperactivity problems in children aged 10–14
M Nobile, M Rusconi, M Bellina, C Marino… - European Child & …, 2010 - Springer
Abstract The functional Val158Met COMT polymorphism appears to affect a host of
behaviours mediated by the pre-frontal cortex, and has been found associated to the risk for …
behaviours mediated by the pre-frontal cortex, and has been found associated to the risk for …
Evaluation of potential gene–gene interactions for attention deficit hyperactivity disorder in the Han Chinese population
Q Qian, Y Wang, J Li, L Yang, B Wang… - American Journal of …, 2007 - Wiley Online Library
Several lines of evidence suggest that attention‐deficit/hyperactivity disorder (ADHD) is a
polygenic disorder produced by the interaction of several genes with minor effects. To …
polygenic disorder produced by the interaction of several genes with minor effects. To …
Allele frequencies of dopamine D4 receptor gene (DRD4) and Catechol-O-methyltransferase (COMT) Val158Met polymorphism are associated with methylphenidate …
A Pekcanlar Akay, Ç Eresen Yazıcıoğlu… - Psychiatry and …, 2018 - Taylor & Francis
ABSTRACT OBJECTIVES: In this study, it was aimed to analyse the relationship between
clinical improvement in adolescents with attention deficit/hyperactivity disorder (ADHD) and …
clinical improvement in adolescents with attention deficit/hyperactivity disorder (ADHD) and …
Family‐based and case‐control association studies of catechol‐O‐methyltransferase in attention deficit hyperactivity disorder suggest genetic sexual dimorphism
Q Qian, Y Wang, R Zhou, J Li, B Wang… - American Journal of …, 2003 - Wiley Online Library
Attention deficit hyperactivity disorder (ADHD) is the most common childhood‐onset
behavioral disorder. Boys are more often affected than girls. Family, twin, and adoption …
behavioral disorder. Boys are more often affected than girls. Family, twin, and adoption …
Association between Catechol O‐methyltransferase (COMT) haplotypes and severity of hyperactivity symptoms in Adults
H Halleland, AJ Lundervold, A Halmøy… - American Journal of …, 2009 - Wiley Online Library
Attention deficit hyperactivity disorder (ADHD) is a common condition in school aged
children world-wide. Moreover, the majority of the affected children will have persisting …
children world-wide. Moreover, the majority of the affected children will have persisting …