Objective: Morphometric studies of postmortem brains from subjects with mood disorders
have reported altered density of glial cells in the amygdala; however, the nuclear regions …

BACKGROUND: Growing evidence supports a pivotal role for the amygdala in the
pathogenesis of bipolar disorder (BD) and schizophrenia (SZ). However, the occurrence of …

BACKGROUND: There are several lines of evidence implicating a glial abnormality in the
pathophysiology of bipolar disorder. Previous studies have reported a wide range of …

Functional imaging studies consistently report abnormal amygdala activity in major
depressive disorder (MDD). Neuroanatomical correlates are less clear: imaging studies …

BACKGROUND: Functional imaging studies implicate the prefrontal cortex and amygdala in
major depressive disorder and bipolar disorder, and glial decreases have been reported in …

BACKGROUND: A previous study reported reductions in glial density and glia/neuron ratio
in the amygdala of individuals with major depressive disorder (MDD), without a change in …

Volumes of basal ganglia in postmortem brains of 8 patients with mood disorders and 8
control subjects without neuropsychiatric disorder were determined. Morphometry of serial …

Altshuler LL, Abulseoud OA, Foland‐Ross L, Bartzokis G, Chang S, Mintz J, Hellemann G,
Vinters HV. Amygdala astrocyte reduction in subjects with major depressive disorder but not …

BACKGROUND: Abnormalities of cortical neuronal organization and reductions in neuronal
somal size have been reported in schizophrenia. The purpose of this investigation was to …

Background Glial cells are more numerous than neurons in the cortex and are crucial to
neuronal function. There is evidence for reduced neuronal size in schizophrenia, with …