Welcome to the online edition of the Journal of Psychiatry and Neuroscience, the official journal of the Canadian College of Neuropsychopharmacology.
Latest Articles
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Reduced neural activation in the orbitofrontal and insular cortex is associated with anhedonia in major depression. It is more pronounced with aversive stimuli during loss processing than it is during reward processing.
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Our latest editorial shines light on the potential brain imaging genetics holds in understanding the largely elusive pathophysiology of neuropsychiatric disorders.
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This meta-analysis found that antidepressants were effective for restricted and repetitive behaviours, global symptoms and different symptom subdomains of autism spectrum disorders. Low symptom severity and adulthood were associated with better outcomes.
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Children with prenatal alcohol exposure show volumetric reductions in the pregenual anterior cingulate cortex that appear to underlie altered behaviour and emotions.
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The mPFC is an important brain region in depression and addiction. Using proton magnetic resonance spectroscopy, this study found that chronic ketamine users have increased glutamatergic activity in the mPFC.
