Frank et al (10) Conceptual definition | — | — | HAM-D > 7 for 2 wks | No longer fully symptomatic, continued evidence of more than minimal symptoms |
Thase et al (12) | 50 outpatients | Mean 37.3 (SD 9.0) yr | HAM-D 6–10 for 2 wks | Not reported |
Paykel et al (5) | 64 inpatients and outpatients | Range 18–64 yr | HAM-D 8–18 | Depressed mood, psychic anxiety, sexual dysfunction, impairment of work and activities |
Opdyke et al (14) | 105 outpatients | > 67 yr | HAM-D ≤ 10 for 3 wks | Depressed mood, psychic anxiety, somatic anxiety, sexual dysfunction, guilt, anergia, insomnia |
Nierenberg et al (13) | 215 outpatients | Mean 40.5 (SD 10.3) yr | HAM-D 8–15 | Insomnia, fatigue, decreased interest and pleasure |
Simon (11) | 225 outpatients | Range 18–80 yr | HAM-D ≤ 7 | Not reported |