Research Paper
Open Access
Load-dependent inverted U–shaped connectivity of the default mode network in schizophrenia during a working-memory task: evidence from a replication functional MRI study
Feiwen Wang, Chang Xi, Zhening Liu, Mengjie Deng, Wen Zhang, Hengyi Cao, Jie Yang and Lena Palaniyappan
J Psychiatry Neurosci September 27, 2022 47 (5) E341-E350; DOI: https://doi.org/10.1503/jpn.220053
Feiwen Wang
From the Department of Psychiatry, Second Xiangya Hospital of Central South University, Changsha, Hunan, China (Wang, Xi, Liu, Deng, Zhang, Yang); the National Clinical Research Centre for Mental Disorders, Changsha, Hunan, China (Wang, Xi, Liu, Deng, Zhang, Yang); the Centre for Psychiatric Neuroscience, Feinstein Institutes for Medical Research, Manhasset, New York (Cao); the Division of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, New York (Cao); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Que. (Palaniyappan); the Department of Medical Biophysics, Western University, London, Ont. (Palaniyappan); the Robarts Research Institute, Western University, London, Ont. (Palaniyappan)
Chang Xi
From the Department of Psychiatry, Second Xiangya Hospital of Central South University, Changsha, Hunan, China (Wang, Xi, Liu, Deng, Zhang, Yang); the National Clinical Research Centre for Mental Disorders, Changsha, Hunan, China (Wang, Xi, Liu, Deng, Zhang, Yang); the Centre for Psychiatric Neuroscience, Feinstein Institutes for Medical Research, Manhasset, New York (Cao); the Division of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, New York (Cao); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Que. (Palaniyappan); the Department of Medical Biophysics, Western University, London, Ont. (Palaniyappan); the Robarts Research Institute, Western University, London, Ont. (Palaniyappan)
Zhening Liu
From the Department of Psychiatry, Second Xiangya Hospital of Central South University, Changsha, Hunan, China (Wang, Xi, Liu, Deng, Zhang, Yang); the National Clinical Research Centre for Mental Disorders, Changsha, Hunan, China (Wang, Xi, Liu, Deng, Zhang, Yang); the Centre for Psychiatric Neuroscience, Feinstein Institutes for Medical Research, Manhasset, New York (Cao); the Division of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, New York (Cao); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Que. (Palaniyappan); the Department of Medical Biophysics, Western University, London, Ont. (Palaniyappan); the Robarts Research Institute, Western University, London, Ont. (Palaniyappan)
Mengjie Deng
From the Department of Psychiatry, Second Xiangya Hospital of Central South University, Changsha, Hunan, China (Wang, Xi, Liu, Deng, Zhang, Yang); the National Clinical Research Centre for Mental Disorders, Changsha, Hunan, China (Wang, Xi, Liu, Deng, Zhang, Yang); the Centre for Psychiatric Neuroscience, Feinstein Institutes for Medical Research, Manhasset, New York (Cao); the Division of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, New York (Cao); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Que. (Palaniyappan); the Department of Medical Biophysics, Western University, London, Ont. (Palaniyappan); the Robarts Research Institute, Western University, London, Ont. (Palaniyappan)
Wen Zhang
From the Department of Psychiatry, Second Xiangya Hospital of Central South University, Changsha, Hunan, China (Wang, Xi, Liu, Deng, Zhang, Yang); the National Clinical Research Centre for Mental Disorders, Changsha, Hunan, China (Wang, Xi, Liu, Deng, Zhang, Yang); the Centre for Psychiatric Neuroscience, Feinstein Institutes for Medical Research, Manhasset, New York (Cao); the Division of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, New York (Cao); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Que. (Palaniyappan); the Department of Medical Biophysics, Western University, London, Ont. (Palaniyappan); the Robarts Research Institute, Western University, London, Ont. (Palaniyappan)
Hengyi Cao
From the Department of Psychiatry, Second Xiangya Hospital of Central South University, Changsha, Hunan, China (Wang, Xi, Liu, Deng, Zhang, Yang); the National Clinical Research Centre for Mental Disorders, Changsha, Hunan, China (Wang, Xi, Liu, Deng, Zhang, Yang); the Centre for Psychiatric Neuroscience, Feinstein Institutes for Medical Research, Manhasset, New York (Cao); the Division of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, New York (Cao); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Que. (Palaniyappan); the Department of Medical Biophysics, Western University, London, Ont. (Palaniyappan); the Robarts Research Institute, Western University, London, Ont. (Palaniyappan)
Jie Yang
From the Department of Psychiatry, Second Xiangya Hospital of Central South University, Changsha, Hunan, China (Wang, Xi, Liu, Deng, Zhang, Yang); the National Clinical Research Centre for Mental Disorders, Changsha, Hunan, China (Wang, Xi, Liu, Deng, Zhang, Yang); the Centre for Psychiatric Neuroscience, Feinstein Institutes for Medical Research, Manhasset, New York (Cao); the Division of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, New York (Cao); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Que. (Palaniyappan); the Department of Medical Biophysics, Western University, London, Ont. (Palaniyappan); the Robarts Research Institute, Western University, London, Ont. (Palaniyappan)
Lena Palaniyappan
From the Department of Psychiatry, Second Xiangya Hospital of Central South University, Changsha, Hunan, China (Wang, Xi, Liu, Deng, Zhang, Yang); the National Clinical Research Centre for Mental Disorders, Changsha, Hunan, China (Wang, Xi, Liu, Deng, Zhang, Yang); the Centre for Psychiatric Neuroscience, Feinstein Institutes for Medical Research, Manhasset, New York (Cao); the Division of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, New York (Cao); the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Que. (Palaniyappan); the Department of Medical Biophysics, Western University, London, Ont. (Palaniyappan); the Robarts Research Institute, Western University, London, Ont. (Palaniyappan)

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Load-dependent inverted U–shaped connectivity of the default mode network in schizophrenia during a working-memory task: evidence from a replication functional MRI study
Feiwen Wang, Chang Xi, Zhening Liu, Mengjie Deng, Wen Zhang, Hengyi Cao, Jie Yang, Lena Palaniyappan
J Psychiatry Neurosci Sep 2022, 47 (5) E341-E350; DOI: 10.1503/jpn.220053
Load-dependent inverted U–shaped connectivity of the default mode network in schizophrenia during a working-memory task: evidence from a replication functional MRI study
Feiwen Wang, Chang Xi, Zhening Liu, Mengjie Deng, Wen Zhang, Hengyi Cao, Jie Yang, Lena Palaniyappan
J Psychiatry Neurosci Sep 2022, 47 (5) E341-E350; DOI: 10.1503/jpn.220053