Article Figures & Tables
Figures
- Fig. 1
Contrast of salience network activity in (A) control women compared with women with anorexia nervosa (control > anorexia nervosa) and (B) control women compared with recovered women (control > recovered). Data are shown in the radiologic convention on a group average anatomic image; cluster p < 0.01 false-discovery rate–corrected.
- Fig. 2
Activity in the (A) salience network (SN) and (B) default mode network (DMN) for individual participants in each group. The z scores reflect activity at the local maxima for the DMN (pre-cuneus) and SN (anterior cingulate cortex). Group comparison significance levels reflect SPM t contrasts, which include multiple comparison correction (see the Methods section). Lines indicate group means. *p < 0.05.
- Fig. 3
Contrast of default mode network activity in control women compared with women with anorexia nervose (control > anorexia nervosa). Data are shown in the radiologic convention on a group average anatomic image; cluster p < 0.01 false-discovery rate–corrected.
- Fig. 4
Contrast of sensorimotor network activity in (A) control women compared with women with anorerxia nervosa (control > anorexia nervosa) and (B) recovered compared with ill women (recovered > anorexia nervosa). Data are shown in the radiologic convention on a group average anatomic image; cluster p < 0.01 false-discovery rate–corrected.
- Fig. 5
Activity in the sensorimotor network (SMN) for individual participants in each group. The z scores reflect activity at the local maxima for the (A) left postcentral gyrus, (B) right postcentral gyrus, and (C) supplementary motor area (SMA). Group comparison significance levels reflect SPM t contrasts, which include multiple comparison correction (see the Methods section). Lines indicate group means. *p < 0.05, **p < 0.01.
Tables
Group; mean ± SD* ANOVA Characteristic Anorexia nervosa, n = 20 Recovered, n = 24 Control, n = 24 F p value Comparison Age, yr 22.85 ± 5.74 30.25 ± 8.13 27.42 ± 6.28 6.41 0.003 Recovered > anorexia nervosa‡
Control > anorexia nervosa†Age at onset, yr 16.15 ± 2.56 16.63 ± 2.43 — 0.40 0.53 Education, yr 14.40 ± 2.39 16.87 ± 2.74 16.62 ± 2.06 6.75 0.002 Recovered > anorexia nervosa‡
Control > anorexia nervosa‡Illness duration, yr 6.76 ± 6.23 5.90 ± 5.21 — 0.25 0.62 Recovery duration, yr — 7.90 ± 6.01 — — — Body mass index 16.03 ± 1.07 20.83 ± 2.37 21.64 ± 1.26 67.37 < 0.001 Recovered > anorexia nervosa§
Control > anorexia nervosa§BDI 24.57 ± 10.45 4.50 ± 4.21 1.12 ± 0.95 84.94 < 0.001 Anorexia nervosa > recovered§
Anorexia nervosa > control§STAI 50.30 ± 9.44 44.96 ± 9.41 32.67 ± 11.79 17.25 < 0.001 Anorexia nervosa > control§
Recovered > control§Harm avoidance 24.00 ± 5.40 15.54 ± 6.47 9.58 ± 3.99 39.25 < 0.001 Anorexia nervosa > recovered§
Anorexia nervosa > control§Reward sensitivity 7.20 ± 3.72 5.83 ± 3.25 4.42 ± 2.84 3.98 0.023 Anorexia nervosa > control‡ Punishment sensitivity 13.15 ± 4.09 6.62 ± 4.14 4.04 ± 1.85 38.72 < 0.001 Anorexia nervosa > control§
Anorexia nervosa > recovered§
Recovered > control†Intolerance of uncertainty 86.60 ± 16.22 55.17 ± 16.07 48.29 ± 12.34 39.90 < 0.001 Anorexia nervosa > recovered§
Anorexia nervosa > control§EDI-2, body dissatisfaction 14.15 ± 8.01 8.54 ± 17.26 1.37 ± 2.14 7.19 0.002 Anorexia nervosa > control§
Recovered > control†EDI-2, drive for thinness 12.80 ± 6.34 4.25 ± 4.50 0.75 ± 1.87 40.80 < 0.001 Anorexia nervosa > recovered§
Anorexia nervosa > control§
Recovered > control‡Medication use, no. Antidepressant 7 5 0 Antipsychotic 1 0 0 Mood stabilizer 1 0 0 Antidepressant and antipsychotic 1 0 0 Antidepressant, antipsychotic and mood stabilizer 1 0 0 Comorbid diagnoses, no. Major depressive disorder 3 3 0 Anxiety disorder 4 4 0 Major depressive disorder and anxiety disorder 6 2 0 Model; t value, p value Network; region; comparison Model 1* Model 2† Model 3‡ Salience network Anterior cingulate cortex Control > anorexia nervosa 4.59 0.030 4.42 0.002 3.85 < 0.001 Control > recovered 3.87 0.039 4.19 0.005 4.39 0.011 Default mode network Precuneus Control > anorexia nervosa 3.58 0.023 3.85 < 0.001 4.91 0.013 Sensorimotor network Left postcentral gyrus Control > anorexia nervosa 5.26 0.028 5.42 0.013 4.40 0.005 Control > recovered 4.51 0.06 4.81 0.026 4.22 0.024 Right postcentral gyrus Control > anorexia nervosa 5.03 0.002 5.21 < 0.001 — Recovered > anorexia nervosa 4.50 0.008 4.43 0.008 — Supplementary motor area Control > anorexia nervosa 4.64 0.008 4.91 0.002 — Recovered > anorexia nervosa 4.46 0.019 4.53 0.018 —
In this issue
Article tools
Related Articles
Cited By...
- No citing articles found.