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Research Paper
Open Access

Genomic variants and inferred biological processes in multiplex families with Tourette syndrome

Jakub P. Fichna, Małgorzata Borczyk, Marcin Piechota, Michał Korostynski, Cezary Zekanowski and Piotr Janik
J Psychiatry Neurosci May 19, 2023 48 (3) E179-E189; DOI: https://doi.org/10.1503/jpn.220206
Jakub P. Fichna
From the Department of Neurogenetics and Functional Genomics (Fichna, Zekanowski), Mossakowski Medical Research Institute, Polish Academy of Sciences, Warsaw, Poland; the Department of Biological Sciences (Fichna), Purdue University, West Lafayette, Ind., USA; the Laboratory of Pharmacogenomics (Borczyk, Piechota, Korostynski), Department of Molecular Neuropharmacology, Maj Institute of Pharmacology, Polish Academy of Sciences, Krakow, Poland; and the Department of Neurology (Janik), Medical University of Warsaw, Warsaw, Poland
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Małgorzata Borczyk
From the Department of Neurogenetics and Functional Genomics (Fichna, Zekanowski), Mossakowski Medical Research Institute, Polish Academy of Sciences, Warsaw, Poland; the Department of Biological Sciences (Fichna), Purdue University, West Lafayette, Ind., USA; the Laboratory of Pharmacogenomics (Borczyk, Piechota, Korostynski), Department of Molecular Neuropharmacology, Maj Institute of Pharmacology, Polish Academy of Sciences, Krakow, Poland; and the Department of Neurology (Janik), Medical University of Warsaw, Warsaw, Poland
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Marcin Piechota
From the Department of Neurogenetics and Functional Genomics (Fichna, Zekanowski), Mossakowski Medical Research Institute, Polish Academy of Sciences, Warsaw, Poland; the Department of Biological Sciences (Fichna), Purdue University, West Lafayette, Ind., USA; the Laboratory of Pharmacogenomics (Borczyk, Piechota, Korostynski), Department of Molecular Neuropharmacology, Maj Institute of Pharmacology, Polish Academy of Sciences, Krakow, Poland; and the Department of Neurology (Janik), Medical University of Warsaw, Warsaw, Poland
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Michał Korostynski
From the Department of Neurogenetics and Functional Genomics (Fichna, Zekanowski), Mossakowski Medical Research Institute, Polish Academy of Sciences, Warsaw, Poland; the Department of Biological Sciences (Fichna), Purdue University, West Lafayette, Ind., USA; the Laboratory of Pharmacogenomics (Borczyk, Piechota, Korostynski), Department of Molecular Neuropharmacology, Maj Institute of Pharmacology, Polish Academy of Sciences, Krakow, Poland; and the Department of Neurology (Janik), Medical University of Warsaw, Warsaw, Poland
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Cezary Zekanowski
From the Department of Neurogenetics and Functional Genomics (Fichna, Zekanowski), Mossakowski Medical Research Institute, Polish Academy of Sciences, Warsaw, Poland; the Department of Biological Sciences (Fichna), Purdue University, West Lafayette, Ind., USA; the Laboratory of Pharmacogenomics (Borczyk, Piechota, Korostynski), Department of Molecular Neuropharmacology, Maj Institute of Pharmacology, Polish Academy of Sciences, Krakow, Poland; and the Department of Neurology (Janik), Medical University of Warsaw, Warsaw, Poland
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Piotr Janik
From the Department of Neurogenetics and Functional Genomics (Fichna, Zekanowski), Mossakowski Medical Research Institute, Polish Academy of Sciences, Warsaw, Poland; the Department of Biological Sciences (Fichna), Purdue University, West Lafayette, Ind., USA; the Laboratory of Pharmacogenomics (Borczyk, Piechota, Korostynski), Department of Molecular Neuropharmacology, Maj Institute of Pharmacology, Polish Academy of Sciences, Krakow, Poland; and the Department of Neurology (Janik), Medical University of Warsaw, Warsaw, Poland
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Article Information

vol. 48 no. 3 E179-E189
DOI 
https://doi.org/10.1503/jpn.220206
History 
  • Received November 9, 2022
  • Revision received January 9, 2023
  • Accepted March 13, 2023
  • Published online May 19, 2023.
Copyright & Usage 
© 2023 CMA Impact Inc. or its licensors This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY-NC-ND 4.0) licence, which permits use, distribution and reproduction in any medium, provided that the original publication is properly cited, the use is noncommercial (i.e., research or educational use), and no modifications or adaptations are made. See: https://creativecommons.org/licenses/by-nc-nd/4.0/

Author Information

  1. Jakub P. Fichna, PhD*,
  2. Małgorzata Borczyk, PhD*,
  3. Marcin Piechota, PhD,
  4. Michał Korostynski, PhD,
  5. Cezary Zekanowski, PhD†,
  6. Piotr Janik, MD, PhD†
  1. From the Department of Neurogenetics and Functional Genomics (Fichna, Zekanowski), Mossakowski Medical Research Institute, Polish Academy of Sciences, Warsaw, Poland; the Department of Biological Sciences (Fichna), Purdue University, West Lafayette, Ind., USA; the Laboratory of Pharmacogenomics (Borczyk, Piechota, Korostynski), Department of Molecular Neuropharmacology, Maj Institute of Pharmacology, Polish Academy of Sciences, Krakow, Poland; and the Department of Neurology (Janik), Medical University of Warsaw, Warsaw, Poland
  1. Correspondence to: J.P. Fichna, Department of Neurogenetics and Functional Genomics, Mossakowski Medical Research Institute, Polish Academy of Sciences, Pawinskiego 5 Street, 02-106 Warszawa, Poland; jfichna{at}imdik.pan.pl
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Journal of Psychiatry and Neuroscience: 48 (3)
J Psychiatry Neurosci
Vol. 48, Issue 3
30 May 2023
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Genomic variants and inferred biological processes in multiplex families with Tourette syndrome
Jakub P. Fichna, Małgorzata Borczyk, Marcin Piechota, Michał Korostynski, Cezary Zekanowski, Piotr Janik
J Psychiatry Neurosci May 2023, 48 (3) E179-E189; DOI: 10.1503/jpn.220206

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Genomic variants and inferred biological processes in multiplex families with Tourette syndrome
Jakub P. Fichna, Małgorzata Borczyk, Marcin Piechota, Michał Korostynski, Cezary Zekanowski, Piotr Janik
J Psychiatry Neurosci May 2023, 48 (3) E179-E189; DOI: 10.1503/jpn.220206
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